Arthritis Centre (Arthritis, osteoporosis, connective tissue diseases)
Basic and Clinical: There is a well-established program in repair of cartilage and bone in the Arthritis Centre. Molecular biology, biochemistry, medicinal chemistry and biomechanical expertise are available. Tissue culture models and animal disease models are utilized routinely for testing. A current focus is on low toxicity abundant, naturally occurring compounds that are chemically modified to provide advantageous properties for the repair of damaged cartilage and bone. There is a related drug-development and discovery program. Also, there are selected clinical research projects and clinical trials.
Epidemiology Research is ongoing in several areas related to rheumatic diseases. The most comprehensive component is in osteoporosis, through the Canadian Multicentre Osteoporosis Study (CaMos). This large study involves nine Canadian centres and approximately 10,000 subjects across Canada and is now in its seventh year.
Advanced post-graduate training, including MSc, PhD or post-MD, is offered through either Basic Science or Clinical Science departments in the Faculties of Health Sciences and Applied Sciences. There are strong links with clinical mechanics, the Human Mobility Research Centre (HMRC), and with pathology and rehabilitation. Undergraduate medical students and post-MDs at various levels of training also have the opportunity to participate in clinical projects including clinical trials, systematic reviews and educational interventions for patients. There is also a long-standing medical consultation and treatment program in arthritis for Native populations based in Moose Factory with excellent research opportunities. For post-MD advanced specialist research training Fellowships in rheumatology are available through the Arthritis Society. The Canadian Arthritis Network (CAN) also provides support for advanced research training in rheumatology.
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